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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCH
All Species:
40.61
Human Site:
Y459
Identified Species:
81.21
UniProt:
P24723
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24723
NP_006246.2
683
77828
Y459
D
E
A
R
A
R
F
Y
A
A
E
I
I
S
A
Chimpanzee
Pan troglodytes
XP_001168420
683
77824
Y459
D
E
A
R
A
R
F
Y
A
A
E
I
I
S
A
Rhesus Macaque
Macaca mulatta
XP_001112585
684
78077
Y459
D
E
P
R
S
R
F
Y
A
A
E
V
T
S
A
Dog
Lupus familis
XP_547844
683
77864
Y459
D
E
A
R
A
R
F
Y
A
A
E
I
I
S
A
Cat
Felis silvestris
Mouse
Mus musculus
P23298
683
77955
Y459
D
E
A
R
A
R
F
Y
A
A
E
I
I
S
A
Rat
Rattus norvegicus
Q64617
683
77928
Y459
D
E
A
R
A
R
F
Y
A
A
E
I
I
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421417
682
77547
Y458
D
E
D
R
A
R
F
Y
A
A
E
I
I
S
A
Frog
Xenopus laevis
NP_001085794
687
78382
Y452
D
E
A
R
A
C
F
Y
S
A
E
I
T
S
A
Zebra Danio
Brachydanio rerio
Q90XF2
588
67303
R418
Y
I
A
P
E
I
L
R
G
E
D
Y
G
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
Y407
E
A
S
R
A
A
F
Y
A
A
E
V
T
L
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
Y482
D
E
S
R
A
R
F
Y
A
A
E
V
T
C
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P87253
1142
127954
Y922
G
T
K
R
A
Q
F
Y
A
A
E
V
C
L
A
Conservation
Percent
Protein Identity:
100
99.8
65.7
97.6
N.A.
97.5
97.3
N.A.
N.A.
86.2
75.4
35.5
N.A.
41.8
N.A.
55
N.A.
Protein Similarity:
100
100
80.6
99.8
N.A.
98.9
98.9
N.A.
N.A.
93.1
85.8
52.7
N.A.
57.6
N.A.
71.8
N.A.
P-Site Identity:
100
100
73.3
100
N.A.
100
100
N.A.
N.A.
93.3
80
6.6
N.A.
53.3
N.A.
73.3
N.A.
P-Site Similarity:
100
100
86.6
100
N.A.
100
100
N.A.
N.A.
93.3
86.6
20
N.A.
73.3
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
39.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
59
0
84
9
0
0
84
92
0
0
0
0
92
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
9
9
0
% C
% Asp:
75
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% D
% Glu:
9
75
0
0
9
0
0
0
0
9
92
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
92
0
0
0
0
0
0
9
0
% F
% Gly:
9
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
9
0
0
0
0
0
59
50
0
0
% I
% Lys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
9
0
0
0
0
0
0
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
92
0
67
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
0
17
0
9
0
0
0
9
0
0
0
0
67
9
% S
% Thr:
0
9
0
0
0
0
0
0
0
0
0
0
34
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
34
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
92
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _